An in-depth review of home ventilator technology, volume-targeted pressure support, and life-support emergency ventilation systems like LUISA and PrismaVENT.
Non-Invasive Ventilation (NIV) has transformed the management of chronic hypercapnic respiratory failure, COPD exacerbations, and neuromuscular conditions like ALS or SMA in outpatient and homecare settings.
Advanced home ventilators such as LUISA provide flexible circuit options (single-pipe with valve, dual-pipe, or leak circuits) and support both invasive tracheostomy and non-invasive mask therapy without compromising patient comfort.
Modern volume-targeted pressure support modes continuously monitor tidal volume delivery, compensating for mask leaks while protecting pulmonary mechanics.

